Metal-on-metal hip replacement devices manufactured by DePuy Orthopaedics, a subsidiary of Johnson & Johnson, were recalled by the Medicines and Healthcare Products Regulatory Agency (MHRA) in August 2010. These devices have been in clinical use in the UK since July 2003. Recalled products include the 'ASR XL Acetabular System', which is a total hip replacement and the 'ASR Hip Resurfacing System', which is used to preserve more of the hip joint. These implants account for around 10,000 of the metal on metal hips fitted in the UK since 2003.